Thursday, November 28, 2019
Bach, Holborne Haydn Comparison free essay sample
Bach had more In common with Hellebore than he did with Haydn. Discuss using studied pieces. Despite all coming from different periods, Bachs piece does have a lot In common with Hellebores Paean and Gaillardia. For one thing, they both mainly have a contrapuntal texture and are for few instruments, whilst Heydays Symphony is, obviously, for a symphony orchestra. Both the Bach and the Hellebore were Intended to be played at home, whilst the Haydn would have been intended to be played in a concert hall.Hellebore lived in a time when it was rare to state which instruments were being written for so the Bach and the Haydn are both written a lot more idiomatically, and they both used musical directions and dynamics, although in Bachs case they were few. Haydn used melody-dominated homophony and Hellebore used five-part polyphony that is mainly contrapuntal, whilst Bach used a variety of different textures. We will write a custom essay sample on Bach, Holborne Haydn Comparison or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page For most of the serenade he uses a two-part texture, as well as using monophonic, and choral passages, for example in bar one, and the segue mainly has a fugal texture.As all three are different It Is difficult to compare which composer of Hellebore and Haydn has more in common with Bach. This also true when studying the structures of the pieces, in that they are all different, but Heydays sonata form Is fairly similar to Bachs binary form, In that binary form In two repeated sections, and sonata form is two contrasting sections with a repetition of the first section. Both pieces revolve around the tonic and the dominant key. The Hellebore paean Is In D major and the Gaillardia Is In D minor; neither of which modulate.In modern times it is common to pick out the top line as the melody, but it was unlikely that Hellebore intended for this to happen, as his Paean and Gaillardia are both contrapuntal. This means that there Is no obvious melody to listen out for, whereas the Bach and the Haydn both have one. Bach wrote his piece at a closer time to Haydn than he did to Hellebore, and this affected the similarity between the places_ Considering the differences between the three pieces. I disagree with the statement that Bach had more is common with Hellebore than he did with Haydn.
Sunday, November 24, 2019
U.S. Economic Warfare during World War II Essay Example
U.S. Economic Warfare during World War II Essay Example U.S. Economic Warfare during World War II Essay U.S. Economic Warfare during World War II Essay The United States has been considered as one of the powerhouse country in the world. Its booming economy and strong leadership have been the epitome of economic and political success. But the U.S. was not always at the top of the heap. In the early 1900s, during the start of World War I, the U. S. economy was largely dependent on overseas trading but when the war broke out; it dramatically halted economic trading because they were no longer able to sell goods to other countries particularly to Britain and Germany (Hardgrove n.p). War had become an inevitable part of the history of the United States. They have engaged in several battles and confrontations with other nations and even with their fellow Americans as well. So far, the U.S. had participated in numerous wars dating back to the civil war to the present Iraq war.However, it was in the First and Second World Wars that the U.S. had a major participation that resulted in the restoration of peace and order across the globe. Also, it was during this period that the U.S. economy both experienced economic escalation and at the same time fiscal recession. It became anà unfavorable situation towards the end of the 1930s when WWI facilitated the manifestation of the Great Depression in the U.S. that resulted to an economy with a huge ââ¬Å"disparity between U.S. productive capacity and the ability of Americans to consumeâ⬠(Kauffman n.p). On the other hand, it became favorable at the time of the involvement of the Americans in World War II that triggered the elimination of unemployment and beginning of the build up of the warfare mass production that moldedà the U.S. economyà to become a potent and robust economy.In the early 20th century, prior to the war, the U.S. was already under recession. For almost 11 years, the economy demonstrated little progress to get out of the fiscal slump. Every incident of recovery was immediately countered with series of economic downfalls that led U.S. to become st agnant. To mitigate the effects of the recession, the government initiated several reforms in the form of the New Deal which had two versions drafted by the administration of President Roosevelt (Vatter 7). Unfortunately, this program was not able to carry out its purpose of reducing the looming unemployment rate. At this time, there were about 8 million Americans who did not have any work to provide for themselves and their families (Schultz n.p). Being an optimist and sugarcoating the situation were the only doable actions left for the government to do in order to mask the reality. The fall of the stock market, depreciation of the value of the stocks and termination of enterprises were just some of the incidents that drained the finances and purchasing power of theà average American (ââ¬Å"The Depression in the United Statesâ⬠). But there came a point when the economy slightly recovered from the economic turmoil. From 1938 to 1940, the U.S. fiscal Depression streak was mo mentarily downgraded into a recessionary status. However, this only caused a more widespread demand for the government to initiate more aggressive economic measures. Economic recovery according to Vatter, ââ¬Å"required much more massive doses of Keynesian medicine (injections of big G) than had ever been applied by the civilian New Deal in order to finally bring full employment.â⬠(11)Generally, the Great Depression was a period filled with all-time high taxes which paralyzed the trading and exporting to neighboring nations that badly hurt the industrial and capital realm of the U.S. economy (Kauffman n.p). But towards the outbreak of the Second World War around the early 1940ââ¬â¢s, government spending for the impending war in Europe and Asia gradually alleviated the effects of the collapse of the economy. From the commencement of the war until its culmination, the U.S. economy had taken advantage of the many fiscal opportunities that transformed the depressed economy int o a booming economy (Vatter 9).The wartime economy had brought dramatic changes in the lives of many Americans. First, full time employment was made available thus raising the ââ¬Å"overall standard of living.â⬠Second, labor union membership expanded from 10 million before the start of the war to 15 million members in total when the war ended, thus making labor union movements more powerful. Third, agricultural profits soared but the quantity of farmers declined because most of them opted to work in city factories. Lastly, the investements made during wartime seemed to have proven the assumptions of Keynesian economics (Modern American Poetry ). U.S involvement in the war ââ¬Å"brought into operation Keynesian deficit spending of sufficient magnitude to end twelve years of mass unemploymentâ⬠(Vatter 14). More so,The stimulating effect of World War II on the US economy is frequently cited as the spark that brought and end to the Great Depression, but it was not just a s park. Defense spending was the difference between the depressed 1930s and the booming 1940s. (Hooks 2)In effect, the economic boost combined with the World War II participation of the U.S. have altered the American society. Government officials were so overwhelmed by the their involvement in the war that they have neglected to launch economic and social reforms needed in order to sustain their fiscal growth. As a result, longer working days were prompted to increase the industrial production. Also, to lessen the possibility of having labor scarcity, the federal government ââ¬Å"ignored laws regulating the employment of children and women.â⬠As a result, the number of school dropouts skyrocketed and about 1 million of them comprised the labor workforce of the entire country. As the government continued to focus on wartime spending, the living condition of most Americans started to decline because of the cutbacks made on the implementation of social reforms. Poverty began to be a concern amidst high wages. It had beenà ââ¬Å"reported that 20 million Americans were on the border of subsistence and starvation and 25% of all employed Americans earned less than 64 cents an hour, while skilled workers often earned $7 or $8 an hourâ⬠(ââ¬Å"The Depression in the United Statesâ⬠).Regardless of the social reform setbacks, civilian employment opportunities remained high as the war progressed. There was a dramatic surge in employment rate in the private and military industry while unemployment fell ââ¬Å"from over 8 million to about 1 million, even as the civilian labor force held constant at about 56 millionâ⬠(Vatter 17). This indicated that the economy of the United States has completely recovered from its recessionary state 5 years ago. Government spending on the warfare had clearly paid off resulting to a historical increase in mass production that produced large amounts of national profits as well as individual disposable incomes and at th e same time have upgraded the labor conditions.The victory of the Allied forces brought peace and order throughout the world. Howecer, in the US, it was a different story. Many believed that since the war was over, production will be lessened since there will be no more need for generating war equipment. But this was just one of the few side effects of the war. However, in the larger scale, ââ¬Å"the war had not only decisively ended the Great Depression, but it created the conditions for productive postwar cooperation between the federal government, private enterprise, and organized labor, the parties whose tripartite collaboration helped engender continued economic growth after the warâ⬠(Tassava n.p).Since the U.S. became an economic powerhouse, American government officials decided to be of help to countries devastated by the war to indirectly show to the world that they are in control of the global economic activities.à They gave financial aid to Europe amounting to â â¬Å"13 billion through the Economic Recovery Program (ERP) or the Marshall Plan from 1947 to 1951.â⬠à Japan also received $1.8 billion in 1945. The Americans linked the economic restoration of West Germany, Great Britain, France and Japan with their own import and export needs to further their economic goals (Tassava n.p).As Alan Milward, an economic historian, had said;ââ¬Å"the United States emerged in 1945 in an incomparably stronger position economically than in 1941 By 1945 the foundations of the United States economic domination over the next quarter of a century had been securedâ⬠This may have been the most influential consequence of the Second World War for the post-war world.â⬠(qtd. in Tassava ââ¬Å"The American Economy during World War IIâ⬠)After the Second World War, the United States emerged as the worlds largest, and strongest, economy. U.S. citizens were assured that their economy will never go back to its depression days. Their fruits of la bor have produced the ââ¬Å"the largest peacetime trade surplus in American history and the gross national product grew to a record $482.7 billion by the end of the 1950sâ⬠(ââ¬Å"United States Economyâ⬠).World War II saved the United States from further economic turmoil. Without it, mass production would have not materialized thus the supply of millions of employment to many Americans would have not at all been possible. It can be surmised that this historical event was a blessing in disguise for the U.S. It served as the catalyst that forever configured the U.S. economic system and the American society. If it there have not been a war, the need to mass produce would not have materialized and that the U.S. could have remained inactive and unproductive for a long time leaving their potentials and resources unexplored.à More so, most Americans benefited and enjoyed the advantages of having a thriving economy. As a result, the U.S. became the center for wealth and devel opment and their way of living have become an international standard that other nations adhere and aspire to achieve. Clearly, the economic warfare of the 1940s have greatly affected the U.S. position as the leading country in the world.Hardgrove, Kristen. ââ¬Å"United States Involvement in WWI.â⬠12 November 2007. 26 May 2008 socyberty.com/History/United-States-Involvement-in-WWI. 57905.Hooks, Gregory. Forging the Military-Industrial Complex: World War IIââ¬â¢s Battle of the Potomac. Chicago: University of Illinois Press, 1991.Kauffman, Kristina. ââ¬Å"Modern American Economic Historyâ⬠. 26 May 2008 http://members.aol.com/kmkauffman/EconRead.htm.Schultz, Stanley. ââ¬Å"American History 102.â⬠1999. Board of Regents of the University of Wisconsin System. 26 May 2008 http://us.history.wisc.edu/hist102/lectures/lecture21.html.Tassava, Christopher. ââ¬Å"The American Economy during World War II.â⬠EH.Net Encyclopedia, edited by Robert Whaples. 26 May 2008 htt p://eh.net/encyclopedia/article/tassava.WWII.ââ¬Å"The Depression in the United States.â⬠Modern American Poetry.à 26 May 2008 english.uiuc.edu/maps/depression/overview.htm.ââ¬Å"United States Economy.â⬠2007. Encyclopedia of the Nations. 26 May 2008 nationsencyclopedia.com/Americas/United-States-ECONOMY.html.Vatter, Herald G. The US Economy in World War II. New York: Columbia University Press, 1985.
Thursday, November 21, 2019
Coursework. Immunoprecipitation Technique Coursework
. Immunoprecipitation Technique - Coursework Example The basic idea behind this technique is the separation of one single protein from a mixture of proteins. This could give us the idea of several characters of a protein such as its relative occurrence in a solution, itââ¬â¢s up and down regulation as well as its affinity for a specific antibody. Technique/Methodology Usually the process of immunoprecipitation can be completed in two ways: in sequential or in one step. Commonly the antibody on which the required protein is supposed to be attached is immobilized on a solid support such as beads. This solution containing the immobilized antibody and the beaded support is then incubated with the solution that contains the protein mixture containing the required protein. Incubation allows the specific protein to bind to then antigen and form a complex. This complex can then be separated from the solution and studied with different techniques such as ELISA or Western Blot according to the requirements. (Pierce Biotechnology 2011) (Pierce Biotechnology 2011) The diagrams courtesy of ââ¬ËPierce Biotechnologyââ¬â¢ show the process of immunoprecipitation starting from preparation of a solid support along with the antigen to the incubation and the formation of the antigen-protein complexes till the precipitation of the required protein. Types There main types of immunoprecipitation are: 1. ... pitation: Same as Chromatin only difference lies in the detection of RNA binding proteins Uses Immunoprecipitation has been useful in many aspects such as, It has enabled the scientists to know the activation of the proteins, their molecular weight and also separate some protein binding molecules too. This technique has also been helpful in detecting the abundance and activity of a protein. Protocols After collecting the required number of cells and washing them in ice cold PBS, the solution was spinned at 1000g at a temperature of 4 degrees. This would help in separating the supernatant fluid. The next step involves the resuspension of the pellet that contains the cells in an ice cold buffer after which the cells are lysed by centrifuge. The supernatant fluid is removed after spinning it again at 13000g at the same temperature for fifteen minutes. Bradford assay is then used to measure the quantity of the protein after the supernatant fluid is removed by spinning briefly. This super natant free solution is then incubated in a cold room with the required amount of specific antibody solution. After the addition of Protein A or G beads to the tube it is again incubated for an hour and then spinned briefly again so that further supernatant is removed. This beaded fraction is then washed with ice cold buffer and spinned to remove the supernatant and the resultant solution is kept for further analysis. BCL-2 Proteins Bcl 2 family proteins have been identified to play a major role in the process of cell death i.e. apoptosis. These proteins play both anti and pro apoptotic roles. Some members of the family are supposed to increase while some are supposed to decrease this process of apoptosis. In this project the interaction of Bcl 2 family proteins with PUMA have been
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